Mu opioid receptors in the medial preoptic area govern social play behavior in adolescent male rats
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چکیده
منابع مشابه
Galanin neurons in the medial preoptic area govern parental behaviour
Mice display robust, stereotyped behaviours towards pups: virgin males typically attack pups, whereas virgin females and sexually experiencedmales and females display parental care. Here we show that virginmales genetically impaired in vomeronasal sensing do not attack pups and are parental. Furthermore, we uncover a subset of galanin-expressing neurons in the medial preoptic area (MPOA) that a...
متن کاملDopamine, the medial preoptic area, and male sexual behavior.
The medial preoptic area (MPOA), at the rostral end of the hypothalamus, is important for the regulation of male sexual behavior. Results showing that male sexual behavior is impaired following MPOA lesions and enhanced with MPOA stimulation support this conclusion. The neurotransmitter dopamine (DA) facilitates male sexual behavior in all studied species, including rodents and humans. Here, we...
متن کاملEstrogen-induced alteration of mu-opioid receptor immunoreactivity in the medial preoptic nucleus and medial amygdala.
The mu-opioid receptor (mu-OR), like most G-protein-coupled receptors, is rapidly internalized after agonist binding. Although opioid peptides induce internalization in vivo, there are no studies that demonstrate mu-OR internalization in response to natural stimuli. In this study, we used laser-scanning microscopy to demonstrate that estrogen treatment induces the translocation of mu-OR immunor...
متن کاملOxytocin in the medial preoptic area facilitates male sexual behavior in the rat.
Oxytocin (OT) is a versatile neuropeptide that is involved in a variety of mammalian behaviors, and its role in reproductive function and behavior has been well established. The majority of pharmacological studies of the effects of OT on male sexual behavior have focused on the paraventricular nucleus (PVN), ventral tegmental area (VTA), hippocampus, and amygdala. Less attention has been given ...
متن کاملEffect of the nitric oxide level in the medial preoptic area on male copulatory behavior in rats.
We investigated the influence of the extracellular nitric oxide (NO) level on male copulatory behavior. We confirmed the changes of nitrite ([Formula: see text]) and nitrate ([Formula: see text]) in the medial preoptic area (MPOA) by administration of the NO precursorl-arginine (l-Arg, 10 mM) or the NO synthase inhibitor N G-monomethyl-l-arginine (l-NMMA, 10 mM) via a dialysis probe. [Formula: ...
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ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2020
ISSN: 1601-1848,1601-183X
DOI: 10.1111/gbb.12662